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Antimutagenic Agents 정의: Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved.
error-prone DNA repair 정의: DNA repair pathways that tend to increase the endogenous mutation rate. [GOC:jl, PMID:11459974]
error-prone postreplication DNA repair 정의: The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication, without removing the replication-blocking lesions, and with an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. [GOC:jl, PMID:11485998]
Pathologic Mutagenesis 정의: Any event, process, or activity that produces a deleterious alteration of DNA. (NCI)